One way that you can treat a wasp nest is by using an insecticide dust for wasps such as Diatomaceous Earth. Use Dr. Diatomaceous Earth kills on contact by causing the pests to dry out and die by absorbing the oils from the exoskeleton of the insect. The pesticide works best if left dry.Click to see full answer. In this manner, can you kill yellow jackets with diatomaceous earth?Boric acid and diatomaceous earth (these are powders) will kill the wasps as will soapy water. If you use any of these you need to apply the material at night (late evening) when the majority of the wasps are in the nest.Also Know, does vinegar kill wasp? White vinegar is a natural and easy alternative to kill wasps. Simply mix a cup of vinegar with a cup of water (or any equal amount) in a spray bottle and carefully spray the offending pests. Then, what kills wasps instantly? Shoot a mixture of 1 tablespoon (15 mL) of dish soap per 1 cup (240 mL) of water. Pour hot water into a spray bottle and add your dish soap. Locate the wasps and spray them until they stop moving. If possible, use a hose-end sprayer for a more direct application.How do you destroy a wasp nest?To destroy the nest, pour soapy water over it, which will drown the wasps. If you can’t reach the nest, use a hose-end spray bottle to spray the nest with the soapy water. You can also try spraying the nest with a pesticide spray or sprinkling an insecticidal dust over it, which will kill the wasps inside.