The short answer is: Yes, it can be safe to drive in 4WD on the highway as long as you’re going very slowly and so does the rest of the traffic around you. In other words, only during severe road conditions that require you to.Click to see full answer. Likewise, people ask, how fast can you drive in 4 wheel drive high? 55mph is it bad to drive in auto 4wd? Re: 4WD Auto Using Auto 4wd will not hurt anything. It is there and available if the truck detects wheel slippage. But, the hubs are free, so it’s not putting extra load on your transfer case. You don’t want to use 4wd high for long distances on dry pavement. Keeping this in consideration, when should I use 4×4 high? Use “4-High” when… you are needing slightly more traction than normal, but can still drive at a reasonably high speed. If you’re going oer 15 mph, then this is the setting you’ll use. In snowy conditions or slippery conditions, rocky roads, or when you’re going oer some rough pasture, this is the setting you’ll want.Is it OK to drive in 4×4 on the highway?The short answer is: Yes, it can be safe to drive in 4WD on the highway as long as you’re going very slowly and so does the rest of the traffic around you. In other words, only during severe road conditions that require you to.